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Specialty Tests

Lyme Disease IgG & IgM Line Blot

Order a Lyme IgG and IgM line blot in Texas. Learn when second-step testing is appropriate, how results are interpreted, and where to collect at Labcorp.

Second-Step Lyme Test

What is included?

Lyme IgG line blot and interpretation Lyme IgM line blot and interpretation Individual Borrelia-specific antibody bands

About this test

The Lyme Disease IgG & IgM Line Blot detects antibodies directed against specific proteins of Borrelia burgdorferi. It reports separate IgG and IgM line blot interpretations along with the individual antibody bands detected.

This test is intended primarily as a second-step evaluation when an initial Lyme antibody screening test has been positive or equivocal. It should not ordinarily be used by itself as the first or only test for suspected Lyme disease.

Results must be interpreted in the context of symptoms, potential tick exposure, the duration of illness, and prior Lyme testing. A positive antibody pattern provides supportive evidence but does not independently determine whether infection is active.

What can this test tell me?

This blood test reports separate IgG and IgM antibody patterns against Borrelia burgdorferi. It is intended for second-step testing after a positive or equivocal initial Lyme antibody screen, rather than as a standalone first test.

How should I prepare?

Have your prior Lyme test result and symptom timeline available for the ordering clinician. Follow the collection instructions supplied with your order before visiting Labcorp.

Common questions

What is the difference between Lyme IgG and IgM?

IgG and IgM are different antibody classes. Their meaning depends on symptom duration and the complete testing sequence. CDC advises disregarding a positive IgM result when illness has lasted more than 30 days. An isolated antibody band does not establish a diagnosis.

Does a positive result mean the infection is active?

Not necessarily. Lyme antibodies can persist for months or years, including after treatment. Antibody testing cannot establish cure; review the result with a clinician alongside symptoms and exposure history.

Read the clinical reference

CDC: interpreting Lyme testing

Collection and results

Collection is currently through participating Labcorp locations only. Wait for your requisition and collection instructions before visiting. Results are delivered through an approved communication method; timing depends on the tests ordered. Contact Rios Click Labs if you need help with result access.

Ordering labs in Houston ยท Find a collection location

How it works

  1. Add this test or panel to your cart and complete checkout online.
  2. Rios Click Labs / Rios Healthcare reviews and processes your order.
  3. You receive collection instructions before visiting a participating Labcorp location. Collection is currently through Labcorp only.
  4. Your results are returned through an approved communication method.

Lab testing does not replace emergency care, diagnosis, treatment, or ongoing medical management. If you have urgent symptoms or a medical emergency, seek prompt medical care.

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